Chapter 11: Micronutrients in Metabolism
11.10 Manganese
University of Hawai‘i at Mānoa Food Science and Human Nutrition Program
Manganese is a cofactor for enzymes that are required for carbohydrate and cholesterol metabolism, bone formation, and the synthesis of urea. The antioxidant enzyme superoxide dismutase also uses manganese as a cofactor.
Manganese deficiency is uncommon, and there is not a clear syndrome that has been characterized. When it has been observed, symptoms have included impaired growth, bone demineralization, and changes to blood cholesterol and/or glucose tolerance. Toxicity is more of a concern with manganese. Occupational exposure has been seen in welders and miners who inhale manganese dust. Toxicity has also occurred as a result of contaminated drinking water. Long-term overexposure to manganese can cause neurological symptoms similar to Parkinson’s disease.[1]
Dietary Reference Intakes for Manganese
Table 11.101 Dietary Reference Intakes for Manganese[2]
Age Group | AI Males and Females (mg/day) | UL (mg/day) |
Infants (0–6 months) | 0.003 | None established |
Infants (7–12 months) | 0.6 | None established |
Children (1–3 years) | 1.2 | 2 |
Children (4–8 years) | 1.5 | 3 |
Children (9–13 years) | 1.9 (males), 1.6 (females) | 6 |
Adolescents (14–18 years) | 2.2 (males), 1.6 (females) | 9 |
Adults (> 19 years) | 2.3 (males), 1.8 (females) | 11 |
Pregnancy | 2.0 | Same as non-pregnant |
Lactation | 2.6 | Same as non-lactating |
Dietary Sources of Manganese
Table 11.102 Some Food Sources of Manganese[3]
Food | Serving | Manganese (mg) |
Pineapple, raw | 1/2 cup, chunks | 0.77 |
Pineapple juice | 1/2 cup (4 fl. oz.) | 0.63 |
Pecans | 1 ounce (19 halves) | 1.28 |
Almonds | 1 ounce (23 whole kernels) | 0.65 |
Peanuts | 1 ounce | 0.55 |
Instant oatmeal (prepared with water) | 1 packet | 0.99 |
Raisin bran cereal | 1 cup | 0.78-3.02 |
Brown rice, cooked | 1/2 cup | 1.07 |
Whole wheat bread | 1 slice | 0.60 |
Pinto beans, cooked | 1/2 cup | 0.39 |
Lima beans, cooked | 1/2 cup | 0.49 |
Spinach, cooked | 1/2 cup | 0.44 |
Sweet potato, cooked | 1/2 cup, mashed | 0.44 |
Tea (green) | 1 cup (8 ounces) | 0.41-1.58 |
- Micronutrient Information Center: Manganese. Oregon State University, Linus Pauling Institute. https://lpi.oregonstate.edu/mic/minerals/manganese. Updated in March 2010. Accessed September 02, 2020. ↵
- Source: Dietary Fact Sheet for Health Professionals: Manganese. National Institutes of Health, Office of Dietary Supplements. https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/. Updated March 26, 2021. Accessed July 31, 2023. ↵
- Source: Micronutrient Information Center: Manganese. Oregon State University, Linus Pauling Institute. https://lpi.oregonstate.edu/mic/minerals/manganese. Updated in March 2010. Accessed September 02, 2020. ↵
Superoxide dismutase (SOD) is a family of antioxidant enzymes that use copper, zinc, or manganese as cofactors. SOD converts superoxide to hydrogen peroxide and oxygen.